Acidic vs. Activated Cannabinoids

Posted: June 4, 2013 in Cannabis, Science

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Over the last few years, I have educated myself on the cannabis plant and its different compounds. Specifically, there are two main compounds that people are familiar with and refer to, and that’s CBD: Cannabidiol and THC: Tetrahydrocannabinol. As you may or may not know, CBD is a non-psychoactive compound versus THC, a psychoactive compound found in the plant. Both of these are the most popular compounds researched that we know of today and are only a couple among thousands of other chemical compounds we have yet to identify in the plant. We recently started doing some reserach on CBC which stands for cannabichromene which is said to act as an anti-inflammatory effect but that remains to be seen.

 The current research suggests that there is a difference between the effects of activated vs. acidic THC and CBD. When these two cannabinoids are heated decarboxylation, also known as activation occurs. As the cannabinoids are activated through decarboxylation, they turn into activated forms of THC and CBD. The heating can occur from vaporizing, smoking, extracting or heating the compound in an edible mixture.  

It is important to remember that the physiological effects of THC-acid and an activated THC are different, and the importance of how each will be used varies from person to person dependent on the ailment being treated. THC-acid which is not activated is non- psychoactive and it will not leave you feeling high. For example, juicing with raw cannabis is known as the THC- acid form; you will get the medicinal effects without feeling intoxicated. This feeling is different from the activated THC, which tends to leave you feeling intoxicated in the head.  

Pure analytics reports that patients report that the benefits, although vary person to person, between the acidic vs. activated is incredible. It seems that people prefer an acidic cannabinoid therapy for the overall balance effect to the endocannabinoid system, over the activated THC therapy.      

People should know that although THC-acid and CBD-acid is favorable over the THC activated, the acidic cannabinoid therapy does not deliver immediate pain relief. If you are looking for immediate pain relief, research suggests you will want activated THC and CBD therapy through heating. Please remember that activated THC is psychoactive and may leave you feeling anxious but neither acidic nor activated CBD will leave you feeling uneasy or intoxicated. 

It’s good to hear that patients are becoming proactive in their cannabis treatment and looking for new ways to treat their ailments. Many patients are turning to a combined therapeutic approach to enjoy the benefits of both acidic and activated cannabinoid therapy.

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